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Issue 12 - A well earned break, what's new and Norton's corner.

Issue 12 - A well earned break, what's new and Norton's corner.
By Pulsenotes • Issue #12 • View online
Evening team!
Welcome to the twelfth instalment of our weekly dose. For those of you who have finished exams, we hope you’re enjoying a well earned break! For those still going, keep it up! You’re almost at the finish line… We’ll help anyway we can with some hidden gems of knowledge wherever you look!
If you’re looking to squeeze in some extra medical knowledge over the summer, you’ll be pleased to hear we’re continuing our LIVE webinar series throughout August and September. We’ll keep you updated on what we’ve got lined up each week!
In this weeks newsletter, we’ll let you know what’s new @pulsenotes and, of course, some more medical knowledge from Norton’s corner.
Enjoy our content? - Remember to tell your friends about us!

What's new this week?
LIVE webinars - what we’ve got coming up…
As you probably know, we’re providing FREE LIVE WEBINARS over the summer.
This week, Ben and Norton are hitting up the webinar scene! They’ll be taking your through some core plastics knowledge and classic neurology cases.
  1. Friday 24th July 11:00 am BST - Pulsenotes LIVE: Plastics emergencies. He’s back, he’s brilliant, he loves plastics. Ben will be guiding you through the 101 of Plastics emergencies.
  2. Saturday 25th July 10:00 am BST - Pulsenotes LIVE: Myasthenia gravis. For the last of his neurology series, Norton will be taking you through an exam classic - myasthenia gravis.
Remember - recordings of all these LIVE events will be available for members that aren’t able to make it!
New stuff…
We’ve just uploaded recordings of the following LIVE events for you to watch at your leisure!
  • Meningitis
We’ve been growing our library and this week we’ve added these:
Norton's Corner
Malaria is one of the most well known tropical diseases worldwide.
Malaria is one of the most well known tropical diseases worldwide.
Malaria testing
Malaria is one of the most well known tropical diseases worldwide. In the UK, malaria is characterised by fever in travellers returning from endemic areas. Malaria is caused by the Plasmodium protozoa, which are transmitted by Anopheles mosquitoes.
Within the UK, malaria is the most common imported tropical disease from patients travelling to endemic areas. The condition can be life-threatening, especially with P. falciparum (most common cause of malaria). Therefore, knowing how we test for malaria is essential for anyone working in healthcare, especially with the increase in global travel (albeit not currently!).
The diagnosis of malaria is based on malarial films (thick and thin slides) and rapid diagnostic tests.
This refers to microscopic examination of a blood film. It remains the ‘gold-standard’ diagnostic tool for malaria. 
A blood specimen is taken from a patient and prepared on a slide using a Giemsa stain. Light microscopy is then used to identify the parasite within erythrocytes. Films are useful in both quantification of the parasitaemia burden and identification of the Plasmodium species. Highest yield of detection is around the time of fever.
Traditionally, a total of three thick and thin blood films should be completed within a 36 hour period to exclude malaria.
Rapid diagnostic tests
These are newer diagnostic tests that can be completed within 15-20 minutes. They involve detection of malarial antigens (e.g. histidine-rich protein 2 or Plasmodium lactate dehydrogenase) in an infected patients blood. It utilises antibodies mounted on a testing strip.
Some rapid diagnostic tests can only detect P. falciparum, whereas others can differentiate between species. They must be combined with films as there are rare cases of false negatives (albeit sensitivity and speciality > 90%) and they cannot quantify the parasite burden. 
Remember, knowing how and why we test for different diseases really helps us in clinical practice! Fever in returning traveller? Don’t forget that malaria test!
Benjamin Norton (@medicalreg)
Final words
Remember to get in contact with any questions, suggestions, or topics that you wish to be covered!
Thanks for reading, remember to tell your friends, and see you next week!
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